ABSTRACT
Military medical equipment develops rapidly in the 10th five-year-plan,but the low utilization rate still widely remains.One of the deep-seated reasons for this problem is the unreasonable element of the establishment system in military medical organization.This paper suggests reforming the military medical organization establishment system boldly,adjusting the existing power of medical service,concentrating the limited manpower & material resource and strengthening the construction of division hospital so as to fully exert the efficiency of medical equipment and improve the ability of medical service support.
ABSTRACT
Objective To establish nude mice model of bone metastasis of breast cancer,and study the best method to evaluate the model.Methods The human breast cancer cell,MDA-MB-231PEGFPN,was injected into left ventricule of nude mice to construct the bone metastasis of breast cancer animal model.Methods of X-ray,whole body optical imaging and pathology were used to evaluate the bone damage after six weeks.Results After six weeks,the result of pathology showed that breast cancer cells had already spread to brain,bone marrow and lung of nude mice.The degree of bone destruction was seen clearly in X-ray,and location of breast cancer cells was observed by whole body optical imaging system.Conclusions The results showed that combined application of X-ray,whole body optical imaging and pathology are the best modalities to evaluate bone metastasis of breast cancer in nude mice.